home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9410o.zip
/
M94A2962.TXT
< prev
next >
Wrap
Text File
|
1994-10-25
|
4KB
|
54 lines
Document 2962
DOCN M94A2962
TI Endoscopy studies of AIDS: the 90's versus the 80's.
DT 9412
AU Bernal A; Frazier R; Del Junco G; Gathe J Jr; Piot D; Special Diseases
Unit, Park Plaza Hospital, Houston, Texas.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):185 (abstract no. PB0170). Unique
Identifier : AIDSLINE ICA10/94369613
AB OBJECTIVE: A comparative study of the endoscopic findings of AIDS in the
90's vs. the early 80's. Those years precluded antiretroviral therapy as
well as most of the primary and secondary prophylaxis of opportunistic
infections. To analyze the impact, if any, of those measures on the
epidemiology and clinical spectrum in GI diseases. METHOD: Retrospective
review of 263 gastroscopies and 226 colonoscopies in 321 HIV+
individuals from 1990 to 1993. Review of data from an earlier study,
demographically comparable with regard to age, sex, and risk factor of
174 patients from 1982 to 1985, is presented as the last percentage in
brackets. Gastric emptying studies were also performed with a mixture of
2 mCl 99mTc sulfur colloid with scrambled eggs. RESULTS: All of the 321
cases reviewed met the CDC criteria of AIDS. There were 318 males and 3
females; mean age was 36.7 years. Risk factors included homosexuality in
303 cases, bisexuals 10 cases, intravenous drug use (IVDU) in 3, blood
transfusions in 2 cases. Candida esophagitis was the most frequent
findings (46 = 14.3% (80's = 23%) Giant ulcer of the esophagus, 6 of
which were CMV proven (26 = 8%) (4%). CMV gastritis and colitis (54 =
16.9%) (6.8%). Intestinal mycobacteria were found in (23 = 7.1%) (1.3%).
Cryptosporidia in (17 = 5.29%) (1.3%); Gastrointestinal KS could be
diagnosed in (27 = 8.4%) (28%); Non-Hodgkins lymphoma endoscopically in
(1 = .3%) (5.7%). Significant delay of gastric emptying manifested by
gastric bezoar, > 200 ml or isotopic studies were seen in (33 = 10.3%)
(0%). CONCLUSIONS: Endoscopic evaluation of AIDS patients continues to
be helpful for diagnosis and proper management. A distinct trend in
presentation seems to be evolving as compared to early years.
Candidiasis of esophagus is decreasing probably due to prophylaxis with
antifungal agents. CMV of the gastrointestinal tract is on the increase
despite specific antiviral agents (gancyclovir and foscarnet). This may
be due in part to viral resistance or different viral strains. KS
continues to decline but this started in mid 80's for unclear reasons.
The increased presence of delay in gastric emptying defies any clear
explanation. Progress in opportunistic infection therapy with longer
life expectancy and more concomitant MAIC infections could be the base,
however, further studies seem warranted. Is the HIV virus itself the
culprit?
DE Adult AIDS-Related Opportunistic Infections/DIAGNOSIS/*EPIDEMIOLOGY
Cross-Sectional Studies *Endoscopy, Gastrointestinal Female Gastric
Emptying/PHYSIOLOGY Gastrointestinal Diseases/DIAGNOSIS/*EPIDEMIOLOGY
Gastrointestinal Neoplasms/DIAGNOSIS/*EPIDEMIOLOGY Human Incidence
Lymphoma, AIDS-Related/DIAGNOSIS/*EPIDEMIOLOGY Male Retrospective
Studies Texas/EPIDEMIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).